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Neuroguard IEP System Receives FDA Approval for Carotid Revascularization.

Neuroguard IEP System Provides
Stroke Protection When It Matters Most

When it comes to carotid stenting, details matter. Time matters. And above all, safety matters. Historically, clinical studies of carotid stenting (CAS) show stroke occurs in 3-9% of patients.1-4  Most strokes are due to embolization during stenting and balloon dilation in the index procedure5, resulting in poor patient outcomes and significantly increased hospital costs.

Integrated Embolic Protection (IEP) platform
Captures emboli others can’t

Neuroguard IEP® System

3-in-1: stent + balloon + filter

  • Designed to safeguard against stroke & cognitive impairment associated with microembolization6-8
  • Proprietary 40 micron filter pores are 3-4x smaller than traditional filters and mesh-covered stents9
  • Physician-controlled filter is adjusted to the anatomy to help prevent particles from passing around the filter
Clinical studies of IEP technology in CAS procedures
have consistently shown unprecedented 99% freedom from strokes.10-12

FlexRing stent technology. Strength + flexibility

Contego’s FlexRingTM technology provides the best of both open and closed cell stents with optimized flexibility AND radial strength.
Traditional closed cell carotid stent
Neuroguard IEP Stent
Explore Neuroguard IEP
INDICATIONS, SAFETY WARNINGS

The Neuroguard IEP System is approved for sale in the USA. Caution: Federal (United States) law restricts this device to sale by or on order of a physician. Prior to use, please see the Instructions for Use for a complete listing of Indications, Contraindications, Warnings, Precautions, Potential Adverse Events, Operator Instructions, and Directions for Use.

 

References

1ACT 1: N Engl J Med 2016;374:1011-20.

2SAPPHIRE Randomized: Yadav JS, et al. N Engl J Med 2004;351:1493-501.

3CREST: Brott et al, N Engl J Med 2010;363:11-23.

4EVA-3S: Mas, Jean-Louis, et al. N Engl J Med 2006;355:1660-71.

5Obeid, et al. J Vasc Surg. 2015 Sep;62(3):616-23.

6Zhou W, et al. Jour of Vasc Surg. 2017 Mar;65(3):686-694.

7Hitchner E, et al. Jour of Vasc Surg. 2016 Dec;64(6):1719-1725.

8Maggio P, et al. Jour of Neuro Sciences. 2013 May 15;328(1-2):58-63

9Per IFUs of devices: Pore sizes of various embolic protection devices: Angioguard 100µm, NAV6 120µm, and mesh-covered stents: CGuard 165µm, Terumo 375µm, Gore 500µm.

10Langhoff R, et al. Catheter Cardiovasc Interv. 2022;100(6):1090-1099.

11Langhoff R, et al. JACC Cardiovasc Interv. 2019;12:395-403.

12Gray W, et al. JACC Cardiovasc Interv. 2025;18(3)367-376

13Kwolek, CJ et al. J Vasc Surg. 2015 Nov;62(5):1227-34.

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This information is intended solely for the use of healthcare professionals based in the United States. For those outside the United States, please contact us.
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Paladin, Neuroguard IEP, Vanguard IEP, Excipio, Integrated Embolic Protection, and FlexRing are trademarks or registered trademarks of Contego Medical.